Do I need my spouse's signature to sell property registered only in my name?

If the property is genuinely your self-acquired property, registered solely in your name, and there's no other legal claim on it (such as it being treated as a shared household under domestic violence law, or a joint family property with other legitimate claimants), you generally don't need your spouse's signature or consent to sell it.

One important exception to be aware of: if the property qualifies as the "shared household" and your spouse (typically a wife) has protection under domestic violence law, she has a right to reside there, and you may face restrictions on dealing with the property in a way that defeats that right, even while litigation is ongoing.

Buyers and their lawyers also often ask for a spouse's no-objection as a matter of practical caution, even where not strictly legally required, simply to avoid any later dispute clouding the title. It would be worth having a property lawyer review your specific situation, including whether any domestic violence or other proceeding is pending, before proceeding with the sale.